Immubact (Lysozyme)

Poultry

Immubact (Lysozyme)

Lysozyme is a ubiquitous enzyme occurring widespread in humans, animals, birds, invertebrates as well as bacteria, phages and plants having diverse role starting from digestion to immune response. They are found in various body fluids, external body secretions like tears, saliva, gastric juices, tracheal secretion and small amounts in internal secretions like serum, pleural fluid and CSF (Cerebrospinal fluid).

Countries around the world have been looking for ways to eliminate the routine usage of antibiotics in animal feed in order to reduce the perceived risk of anti-microbial resistance in human and animal populations. Lysozyme has been widely recognized for its antibacterial and antifungal properties. Used to support already-existing immune defenses to fight bacterial infections.

Lysozyme, a natural anti-microbial enzyme, can be used as a replacement for antibiotics in chicken feed. Number of studies showed that the enzyme permitted the same level of infection resistance as is normally obtained with pharmaceutical antibiotics.

Mode of Action:

Lysozyme is a polypeptide enzyme consisting of 128 amino acids cross-linked by 4 disulfide bridges and functions by attacking peptidoglycans (found in the cell walls of bacteria) and hydrolyzing the glycosidic bond that connects N-acetylmuramic acid with the fourth carbon atom of N-acetylglucosamine.

The beta (1-4) glycosidic bond between N-acetylglucosamine sugar (NAG) and N-acetylmuramic acid sugar (NAM) to be hydrolysed during the Immubact (Lysozyme) reaction are circled.

It does this by binding to the peptidoglycan molecule in the binding site within the prominent cleft between its two domains. This causes the substrate molecule to adopt a strained conformation similar to that of the transition state.

Dosage:

Poultry - 100 to 200 ppm via feed route OR 1g/5 litre water every day up to 42 days.

Read 1404 times
More in this category: « RAPID PROTEASE

Enquire Now

Select Your Location